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Research Support Specialist IV
Charles River Laboratories in Bethesda, Maryland
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Date Posted April 14, 2019
Employment Type Fulltime
Application Deadline Open until filled

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

We are seeking a Research Support Specialist IV for our Insourcing Solutions site located in Bethesda, MD.

The following are responsibilities related to the Research Support Specialist IV position:

The following are minimum qualifications related to the Research Support Specialist IV position:

  • Perform genome modification of mice via CRISPR/cas9 microinjections in embryos to create gene Knock out and gene knock in animals, production of transgenic mice via pronuclear injection.

  • Perform injections of gene targeted embryonic stem (ES) cells into blastocysts to create chimeric mice.

  • Assist with the cryopreservation of mouse germplasm, including freezing and storage of sperm.

  • Rederive of lines from frozen embryos and sperm via in vitro fertilization, maintaining of animal colonies to augment the existing cryopreservation and rederivation program.

  • Provide rodent genotyping assistance by collecting samples from gene modified animals.

  • Prepare tissue, and germplasm samples for transport and storage utilizing liquid nitrogen.

  • Maintain integrity of the embryo rederivation efforts, including detailed accurate record keeping and routine breeder observations.

  • Ability to work flexible hours and with other team members to ensure research needs and experiments are carried out to comply with appropriate timelines.

  • PhD degree with 3 to 5 years of lab experience in molecular biology, genetics, biochemistry or related fields

  • Must have experience in applying genetics knowledge to the laboratory animal field relating to genetically engineered mice (GEM) including embryo manipulations, gene targeting in embryonic stem (ES) cells and development of gene constructs for production of GEM.

About Insourcing Solutions

Charles River Insourcing Solutionsâ„  can streamline research by delivering operational and cost efficiencies through the strategic insourcing of GMP, GLP and non-GLP research services from discovery through safety assessment. Insourcing Solutionsâ„  provides you with the ability to maintain control of your facility and expertise while leveraging available space.

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