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Principle Scientist
Emergent BioSolutions in Gaithersburg, Maryland
 
 
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Date Posted April 12, 2018
Category
Science-Biochemistry
Employment Type Fulltime
Application Deadline Open until filled
 
 
 

Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect, innovation and growth opportunities. Here, you will join passionate professionals who advance their scientific, technical and professional skills to develop products designed-to protect life.

The Principal Scientist is responsible for support, design and application of manufacturing and purification processes for the production of protein vaccine candidates.

 

Responsibilities

Oversee the scientific projects with the down stream process group.
Development of scalable chromatographic techniques for the purification of protein candidates.
Consolidation of purification steps for the construction of purification processes.
Optimization and scale-up of purification processes for transfer to a contract manufacturing organisation for GMP manufacture.
Assist in the technical transfer of purification processes to a relevant CMO.
Invention of suitable in-process controls in order to follow the purification process.
Generation of technical documents capturing the construction of purification processes.
Technical review of draft batch manufacturing records.
Generation of draft IPC protocols.
To perform intellectual property sign-off and scientific review of Emergent generated data.
To communicate ideas and experimental designs with colleagues and manger.
To monitor and communicate progress and highlight delays or potential risks to project timelines.
To report on progress on a regular basis, both within the downstream group and other vaccine programme teams.
Actively train other members of the process development and manufacturing team in purification techniques.
Job Resquirements

PhD in Biochemistry or related field with a minimum of 8 years experience.
In-depth knowledge of purification and filtration techniques.
Experience of working at both lab and manufacturing scale.
Knowledge of fermentation (eukaryotic and prokaryotic systems) and analytical techniques.
Ability to solve complex and varied problems independently
Experience with analytical data analysis.
 
Emergent BioSolutions is an Equal Opportunity/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, gender, age, national origin, disability, Protected Veteran status, sexual orientation, or any other characteristic protected by federal, state or local law.

Information submitted will be used by Emergent BioSolutions for activities related to your prospective employment. Emergent BioSolutions respects your privacy and any use of the information submitted will be subject to the terms of our Privacy Policy .

Emergent BioSolutions does not accept non-solicited resumes or candidate submittals from search/recruiting agencies not already on Emergent BioSolutions’ approved agency list. Unsolicited resumes or candidate information submitted to Emergent BioSolutions by search/recruiting agencies not already on Emergent BioSolutions’ approved agency list shall become the property of Emergent BioSolutions and if the candidate is subsequently hired by Emergent BioSolutions, Emergent BioSolutions shall not owe any fee to the submitting agency.

 

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